Just as the title says, this could be a spoiler (idk if speedrunners even care about spoilers...), all of the tips I'll put in here came from TheSuicineFighter, Naivist, EazySpeezy, and Shandy00's submitted runs!
Edit: hello mr/mrs moderators delete the thread if needed to,
This is like a super small note that contains small little words that can make big improvements in the run.
The best run to do is;
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Meathouse Ending Toolbox, Safe, Battery, Family Tape, Signals, Sam, Yes, Rotting Tape, Yes
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No Help Kitty Ending Flower, Kitchen Tape, 325, Peach Pie, Meat Pie, Neighborhood Tape, Facade > Re-continue, Toolbox, Sam, No
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No Secrets Ending Kitchen Tape, Apple Pie, Gift/Present Tape, CBF, Accident Tape, Nobody > Re-continue, Water Bucket, Robot, Key, Secrets Tape, No
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Yes Secrets Ending/Humanoid Ending Water Bucket, Robot, Key, Secrets Tape, Yes
If the words still feel a bit unknown; I'll make another forum explaining how these little words work, as it is too much to be explained, but if you know what it means, then you've got yourself some luck! Have fun speedrunning!