Woo, finally got a decent run with a decent boss. Wasn't exactly the cleanest boss fight, but it will do.

The biggest time save I was able to find from Oreo's run was in the "thwomp" room, where at 9:17​ I was able to cheese the thwomp to immediately go right, saving about 10 seconds.

I suspect a sub 16 minute run is theoretically possible, but actually getting the RNG in the boss would be really unrealistic and painful.