I'm really late but I'm implementing this now.

I made a segmented run as a compilation of all the improvements discussed here and some new ones as well.

Found another minor improvement and this can be used in regular any% runs. Saving and loading right after getting lab key skips having to travel back which saves around 4s.

I found a minor improvement. Getting 2-3 good tips form joe's pizza at the start allows you to get the skate board before working at stickbucks. This saves 6-8s which is just enough for a 2.3x I think.

I came up with some modifications to the rout though the RNG required is just too much for normal runs. Anyhow here is a example run. Money required can be obtained if get 1700 at stickbucks and win that horse race.

About lab to my knowledge theoretical fastest lab using the glock is 53s in that example run lab took 63s so there is 10s of theoretically possible time save.

Not related but for anybody asking why my 4:15 run disappear I accidentally put a link for my 4:59 in the submission. That is the correct video.