Hi, my name is Riuzaki and I will try help new players start beating class challenges with reasonable time and consistency. This guide is in progress and I will modify it based on my personal experience.

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Druid vs Grand Widow Faerlina

Mulligan: Innervate, Echoing Ooze, Haunted Creeper, Nerubian Egg, Mark of the Wild.

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Rogue vs Maexxna

Mulligan: Voodoo Doctor, Elven Archer, Defias Ringleader, Echoing Ooze, Murloc Tidehunter, Sunfury Protector, Razorfen Hunter.

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Hunter vs Loatheb Mulligan: Webspinner (do not waste time mulliganing, because your deck contains only webspinners).

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Mage vs Heigan the Unclean

Mulligan: Nerubian Egg, Mad Scientist, Kirin Tor Mage, Duplicate, Loot Hoarder (if Nerubian Egg or Mad Scientist not in hand).

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Shaman vs Gothik the Harvester

Mulligan: Rockbiter Weapon, Flametongue Totem, Haunted Creeper, Nerubian Egg, Earth Elemental, Shattered Sun Cleric (if Haunted Creeper or Nerubian Egg in hand).

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Warlock vs The Four Horsemen

Mulligan: Voidwalker, Unstable Ghoul, Imp Master, Voidcaller.

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Warrior vs Grobbulus

Mulligan:

• One 2-mana card. In order of preference: Fiery War Axe, Amani Berserker, Unstable Ghoul, Armorsmith;
• One 3-mana card. In order of preference: Raging Worgen, Frothing Berserker, Tauren Warrior, Acolyte of Pain;
• One of Death's Bite;

Tips:

• Try not to leave minions at 1 hp, because of his hero power;
• Fastest wins often include Fiery War Axe start and unchecked Raging Worgen;
• His strongest play is Echoing Ooze + Mutating injection (2x 5/6 with taunt for 5 mana). He plays 4 copies of each in his deck;

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Priest vs Thaddius

Mulligan: Zombie Chow, Nerubian Egg, Dark Cultist, Shadow Madness, Lightspawn, Auchenai Soulpriest (if no Lightspawn in hand).

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Paladin vs Kel'Thuzad

Mulligan: Avenge (with Echoing Ooze), Echoing Ooze, Scarlet Crusader, Aldor Peacekeeper, Sword of Justice (if Echoing Ooze in hand and no 3-drop in hand).