Found an interesting bug - if you use the 3 point physical damage canticle after the 9 (or 6) point canticle, the 9 damage stays applied until the end of the entire mission. Used that to power through a lot of fights and lucked into an early set of flamethrowers (hence swapping the first two bosses around - they're really handy against the Vanguards in the Lord Astronomer fight). Have not looked into any other canticles and if they have lingering effects too. If the other canticles behave the same way, then there's a lot of variation in strategies possible.

The splits were a bit messed up, so the running total shows lost and gained times in weird ways, but the final time is the only one that matters, eh?

Still a lot of optimizing to do - could go through and find all of the quickest missions, since there are a bunch that I haven't even tested out, and a couple of the missions I did do were 3 fight missions. Additionally, I entered a red fight that I didn't have to in From the Mouth of Malediction. I think using that canticle bug with cleaner play and some route optimization, the time could come down a lot.

Also found another bug/exploit, but unsure if it will save time or not. Still figuring out what to do with it. I'll share what it is once I've played around with it a bit. I don't think it'll shave too much time off, but who knows.