I wrote to the creator of fracuum Tyler Glaiel and asked him if the boss had a pattern. he gave me the disappointing information that the final boss was pure randomness. I do not know if the rest of the enemies have a pattern or are random but I taught that this info might be useful.
Here are his own words: It's purely random. just tank him and shoot him from the inside to speedrun it.
To get the perfect RNG would be him stying up top for 5 turns in which you hit him 5 times each time. However since he always starts at the top and quicly makes his first move its more often 6 turns. This could be reduced to five if we found a way to guarantee 6 hits per turn but I digress.
This means that the probability of a perfect boss RNG and hence a viable run is 1.56% a.k.a 1.5 times out of 1000 runs