Some one should be able to take this to about 10 minutes or lower with all hot key use. I use the fast auto battle hotkey here ("z") to great effect.

The strategy early game is pretty much the same as an Any% run, be a telepathic race, refit ships with crazy laser mods, and mindcontrol your AI opponent down to a single planet. They won't bother you after that.

I use two AI opponents in a small galaxy in order to quickly expand. Basically the goal is to have access to 3 home worlds for building your end game ships and completing research. I got that this time, no caveats after 15 attempts.

For mid game, I tried something new. I researched up to Titans, Dimensional Portal, and Stellar Converter - the end game tech you need to beat the Antarians. I used some Titans with this to down the Guardian.

Then if you don't get the Damper Field or Xenonutrium Armor from Orion, you need to research some shield upgrades. With those, a fleet of 12-15 titans or so should be able to take down the Antaran home world. Just make sure to use the Stellar Converters on the main station first if you're closer to the 12 end of the spectrum! Sometimes the AI doesn't target it until everything else is dead for some stupid reason...