After the initial 4 in the beginning area I have noticed that you only need to fight certain characters and I have found a certain order that works best.

Red (almost any loadout will work) Bouncer (Heavy Punch, Lil Sip, Your Opponent Loses Half Their Current Health) Eoris (Lil Sip, Thorns, Muddle, Bounce) Cal (Interpretation, Your Opponent Suffers One Damage) Wally (Lil Sip, Fireball, Your Opponent Suffers One Damage, Interpretation) Leodora (Curse, Lil Sip, Your Opponent Suffers One Damage, Interpretation) Gresh (Resilience, Your Opponent Suffers One Damage, Your Opponent Loses Half Their Current Health, Interpretation) Bully (Same as Gresh but most loadouts will work)