This should save a few seconds if optimized.

Familiarizing yourself with difficult levels and practicing their shortcuts is a good start to improving your time. I'd also start routing the best toppins to skip for Any% (and skipping Oh Shit! entirely).

DerikLF and I's True Ending route gets every toppin in Oregano Desert in favor of skipping the tomato in R-R-Freezerator. The rest of the routing is the same as Peppino's.