Please show that you have 60 FPS in the PC config setting before you start your run (to prevent "pay to win" for people with faster PCs having faster loading/speed by default and it would be unfair to those who can't hit higher FPS counts). This will even the playing field for everyone.

All Endings speedrun - start from a blank state (delete your save games), save the clear file to a separate (new) save. This is non-negotiable and failure to do so will make your run invalid.

Alternate Ending and Go-Home Club Ending - you do not have to start from a blank state, but loading a save not made in the current run is forbidden, so starting from a blank state is recommended.

No DLC runs - disable any and all DLC before you start the run. Failure to do so won't make your run invalid, but it will be moved into DLC category and renamed as such.

Failure to comply with any of these guidelines will end up in rejecting your run from the leaderboard.