I'm playing through the game and got a softlock late into the sewers bit where you go to find Sanctuary. The three red switches you use to open a door aren't activating for me and aren't clickable at all.

Is there any way around this besides starting the entire game over?

sorry for the late response, did u go and find adams head before going into the sewers? if not yeah might need to start over. lucky its not too long of a game.