General Notes:

Before starting the run make sure to disable Auto Save in the option so you can skip the saving, this doesn’t work in Chapter 25

You can save 2-4 seconds each with early cutscene skips in a lot of places when you good at spamming the Start button

Fastest route is with Submachine Gun but Guitar may easier to start with both route have chapter 8 rain rng should it rain when you meet George and Emily in the parking lot you reset or you just run into the hotel and sleep for 24h until it’s stop raining make sure you have food should that happen

In Chapter 12 when you follow willy there’s a chance that you food gauge is empty at the start of the scene so instead of resetting you can grab some food earlier in the game

Should you run out of Magnum ammo during the Kaysen fight there is some in the wooden boxes on the platform in the third fight

Reloading your weapons in the right situation can save a lot of time