The current categories are pretty silly.
Playing up to the Dragun doesn't make very much sense, as it's not the real final boss. It's similar to playing up to the heart in Issac if you are familiar with that game. However, we already have people running this so we may as well keep it around as a category.
This is my proposed category list: (and the reasoning for each one)
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Kill Dragun: It's the final boss when you first start the game, and people are already running it.
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Kill the past: This is the true ending, though only the first four characters can do it. It seems that the secret characters will likely get pasts in updates though. Each character has a different past, so setting character choice as a sub-category is especially important here.
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Hell: Bullet Hell is the secret final level. This is similar to the Chest in Issac if you are familiar with that game.
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6 Characters: There's no reason to have both 4 and 6 character runs. Also these runs should go to Hell, not just the Dragun, as the Dragun isn't the real final boss no matter which path you take. We could potentially do 6 Character past runs once/if the secret characters get pasts.
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Boss rush: This is an alternate gamemode. (and we already have this category)
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Blessing of the gun: This is another alternate gamemode. It limits you to one gun but makes your gun randomly switch all the time.
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Tutorial: This is a bit silly, but I'd like to run it. (no rng) If this is added it should be a misc category.
I don't think it's worth having a shortcut category.
I don't think it's worth adding an extra category just for glitched chests as they're so rare. We could possibly allow them in multi-character runs.
I think character choice should be set as a subcategory, because runs can be fairly different with different characters. (Bullet in particular is way faster than every other character.)
Another category worth considering is a "full game" run, doing abbey of the true gun and then continuing down to hell.