Okay so I was playing through Golden Dragon GP and I was playing on the 64th floor in the final room of the floor. You know the guys with the swords, there are 3 of them and you can get to the end of the level after you kill them. I was playing as Bad Girl. I accidentally was able to bring the glitch barrier down after only killing the second guy. I had the Physalis Chip on and the smoke coming from the can was right over where the sword guys spawn. and when I killed the second sword guy the third guy was just spawning in. And then the glitch barrier drop. I was also playing on Sweet mode.

Again restated in simpler terms. I had the smoke from the Physalis Chip overlapping with where the word guys spawned in, killed the second guy as the third spawned in and ran through the door not having to kill the third guy. Bad Girl, Golden Dragon GP 64th floor, Sweet Mode.

I think I figured it out. I replicated it in the second to last room in the left most room of Floor 64 today. With the big buff boy and exploding enemies. Well I was playing as Travis on sweet mode and nothing else specials really. I killed the second to last exploding guy while the last exploding guy was spawning in and the barrier dropped. I think if a single enemy spawns in while there is still one enemy left if you kill them while the game while the enemy is spawning it tricks it into thinking you killed the last enemy was killed dropping the barrier. Also weird little dumb thing. I think I noticed that in some instances if I paused and unpaused in a room where enemies have a staggered spawn they would spawn immediately instead of having to wait for them to spawn. But it was inconsistent and weird.