Many speed games tend to have fresh files as the main category followed by NG+ runs.
Shadow Complex Remastered is very picky at the moment and it isn't as simple as going to the menu and make a new file.
For Xbox 360, the experience points data and Gold Weapons Room unlocked flag are saved towards your gamertag. So a fresh file run requires making a brand new gamertag everytime.
As of 12th Dec 2015, I think fresh file runs by making new gamertags is very likely to be doable on PS4/Xbox One but for PC, that's another story. I have heard some players getting corrupted save files as the only way to start off a new run fully fresh but hopefully there is a better way to not only make fresh files but very quickly as well.
I experimented around trying to create a save manager & got my progress reset (in that I lost gold room, but I still had my level). There is a cloud save element, which you can disable with flags according to https://www.reddit.com/r/SteamController/comments/3vfx06/configuration_guide_shadow_complex_remastered/
So ¯_(ツ)_/¯
"my progress reset (in that I lost gold room, but I still had my level)."
The weirdest thing is, that happened to me as well without even making/trying out a save manager.
Ok I found it.
Testing on a dummy account, which I need to complete to test fully, but so far I was able to "reset" the account & restore the save. You have to move your profile at Documents\My Games\Shadow Complex\EmpireGame<user-id> to <user-id>-backup or whatever, then go offline with the flags and bam.
By simply copying the folder back, I got all the tiny amount of progress I made back, but I need to test how it handles gold bar room.
EDIT: I am also able to use this to just straight up copy my main save/profile over to this, so fresh file runs are feasible, as are practice saves.
EDIT 2: Copying the save gives me all the perks except gold room, so that could make practice saves awkward.