Hi.

I'm interested in running this version of Dr. Mario but I've never run a N64 game before and I'm not sure if using emulator is okay. However, seeing that there are a few runs done with emulator on the leaderboard, I assume that it is allowed. So, my question is, which emulator should I use, and are there any settings that I should be aware of?

Use of emulators is allowed. However, I am not familiar with emulators, so I don't know the details. Sorry. I think that emulators that are widely used in general will be fine.

I use Project64 Ver. 2.3.2.202

Project 64 V1.6 is usually the emulator most 64 leaderboards allow, I don't know much about emulating Dr. Mario 64, but this version is worth trying if you can get it.