What's the verdict on using Dragon Orbs for 100%/ any% runs?

The orbs makes the secondary clear easier to obtain, possibly resulting in faster times, however you can only enable them from the episode select, and it's a real grind to get a bunch of them, since you need Shenron wishes.

The moderation team has decided to ban the usage of Dragon Orbs in runs for reasons such as:

They are specifically used for the "what-if" scenarios known as Secondary Clear Conditions.

Dragon Orbs are used to lower the difficulty of the match so you can clear these conditions easily. However, each one is immediately spent after use.

in order to finish Canon% needs you to complete all requirements for completion

the amount of time trying to collect them can take long periods of time.

They Orbs also warn This doesn't count as a Victory before you use them.

On top of the painful Grind just to start a run would kill the fun of the runs over all.

To expand on some of these points -- The appeal of 100% runs is in the routing and execution of the difficult what-if path conditions, and the use of dragon orbs would trivialize this a bit too much since they essentially guarantee you can take the alternate path.

Since you only get one dragon orb per Shenron summon, which as you mentioned takes a ton of time to collect them for run attempts, it would harm the accessibility of the category if you were required to use them in order to get top times.