Just wanted to share a time save I wasn't aware of until yesterday. This was particularly important for Console and Emulator runners, but now it's relevant also for PC runners.
Basically the IGT keeps running until the FMV with Regina entering the portal begins. Between that FMV and the last door there is one FMV that can be skipped. I'm talking about the FMV showing the mainframe falling on Paula. If you skip that cutscene you can save up to 6 seconds.
Watch this video below as reference: You can see at 51:07 the IGT is still running and that cutscene can be skipped.
I hope this is useful for someone.
I actually knew about this and never thought to mention it. I actually never do it either because I never knew it contributed to the IGT. Good to know it actually helps