Inner Sanctum is perhaps one of the most technical mazes in this game because of the snakes that linger at the top of the maze. If you attempt to pass through them while they're awake, they will kill you. This involves getting a flute to put the snakes to sleep. You won't survive all three sections in one go, but it gives you enough time to clear portions of those maze sections away.

If you're low on lives, play conservatively and clear it out quickly as you normally would, especially on the harder difficulties (Can still be done on Hard, if you're crazy.). However, if you have lives to spare, you can death abuse and save from having to get another flute. This saves a total of 7-10 seconds.

If you play to the right, be wary of ghosts in the water. In either case, odds are, Blinky will follow you. Do not jump close to the elevator, or he'll end up going into the water instead of you.