To finish out the main categories I think we should add the customized playthrough, because it is definitely different from quick play because you can choose your character, backstory, and god. I have a crazy run ready for it.
I think customised playthrough shouldn't be a category because runs would be way too differents but instead, we should maybe find some of the best seeds and put them as misc categories.
I think custom should stay a category as it's actually consistent in terms of your character. I just think we need to decided on the appropriate difficulty of the run. Because the variance and timeloss between difficulties can be substantial. We can have sceptic, harbinger, and cultist runs all mingling in the same category
I like the idea of having set seeds for custom runs but we def need a set difficulty too
echoing what gametime said, i also really enjoy the idea of a set seed% run for customs, and randomized seed for customs. the difficulty would need to be agreed on which will be difficult, but the concept of seeds allows for really interesting runs