I found a glitch while shiny hunting where it despawned all pokemon and essential NPCs. You can exit the zone after doing the glitch, but the area remains permanently "Ghosted." I doubt its super useful, considering how hard the game is to break, and possibly even been discussed before.

For those interested in replicating, I fell into the water while in a multi-battle with drifloons(again, I was shiny hunting with outbreak method), and drowned while it was the drifloons turn to attack. When it respawned me on the rock, my screen was in the damaged state, but had 0 access to my pokemon and my useable items with ZR. I could access the map, but couldn't fast travel: I also had access to my inventory screen and settings, but not to saving and the "Lost and Found/Mystery Gift" screen.

Regardless, thanks for putting up on awesome times! I like watching speedruns while shiny hunting so i figured I'd see if this had any implications.