I have successfully used AutoSplit to automatically segment/reset runs based on what's on screen. It's clunky but it makes running the game less stressful for me. Here's a few of the masks I'm using, for demonstration purposes.

I have the run reset when the top-left album slot is empty, so I can quickly recover from false starts. I kept the help text in this image but if you play the English version you might want to change that. The file is named 001_reset.png

I then use this image of a new file being created to mark the start of the run, named 002_start_auto_splitter{b}.png with the {b} flag telling AutoSplit to start the timer not when the screen matches this, but rather when it no longer does.

I then mostly rely on bookmarks for split detection. I use a dummy split image (with the {d} flag in the file name) that has the current page's bookmark, followed by a true split image where the bookmark has vanished because a cutscene is playing or I've left the page.

003_blue_eyes{d}.png

004_blue_eyes.png

I exceptionally detect the appearance of the red-eyed statuette since it has no cutscene.

005_red_eyes.png

To detect the return trip to a page, I include the unlocked bookmarks in the image for good measure.

013_yellow_eyes{d}.png

I end the run when the final cutscene starts, again with a dummy split for the bookmark followed by a real split when the bookmark vanishes. Technically this will stop the timer a bit late, after the statuettes have fallen in place, so you'll have to manually check the end time on a video recording before you submit a run.

018_treasure{d}.png

018_treasure.png

Feel free to ask if you have question or to post your own recommendations. And to look for me off-site if needed, again I run this game like, a handful of times every year for some reason, so I don't check this site often.