All is in the title ;)

BizHawk, RetroArch and other libretro-genesisplusgx front ends are currently the best choices. Fusion and Gens are still accepted, but deprecated. I don't know enough about RomStation, but rom hacks (FR translations) are obviously not accepted.

OK thx for fast answer and see you soon :)

I don't know why but i use genplus-gx on bizhawk emulator and the game go impressively faster in submitted runs than mine :(

Maybe it runs at different speeds on different computers (which is obviously really, really bad)? Some sort of clear comparison would be nice, but it's hard to find places that are identical in different runs. The autoscroller with large tables maybe?

Here are some comparisons. I don't like this. Protip: You can adjust the start of each YouTube video with , (comma) and . (period).

Dining room http://viewsync.net/watch?v=ydP6EChIGL4&t=735.98&v=-BuJbXH7XD4&t=775.34&v=y8PAuUoyJKo&t=739.27&v=8tEsPMOEqSg&t=746.47&mode=solo

Carpet ride https://viewsync.net/watch?v=ydP6EChIGL4&t=316.68&v=-BuJbXH7XD4&t=359.43&v=y8PAuUoyJKo&t=322.86&v=8tEsPMOEqSg&t=326.96&mode=solo

Space flight http://viewsync.net/watch?v=ydP6EChIGL4&t=593.23&v=-BuJbXH7XD4&t=631.4&v=y8PAuUoyJKo&t=596.22&v=8tEsPMOEqSg&t=603.03&mode=solo

Yes, i timed some auto-scroll like mirors section or champaign flight and it's really really slower in my runs (of several seconds) :/ ; i just wanted to know how to ajust/setup the emulator to get the best results.

Did you make sure you're running the NTSC/US version and not PAL/EUR? Might be a stupid question, but it happens.

Not a stupid question at all because i'm rookie in speedrunning and i was running on Europe Version of course... :p Sorry for disturbance et great thanks for the info :) i would try it quickly!

OMG!!! OK... The difference is just incredible o_O Thank you very much for tour help ;)

Hi Tenebrae! I don't understand why my run has been rejected :( I don't used savestate during the run but only to reset. I loadstated to be on start screen and i pressed quickly successively start and R2 (start split button mapped on my joypad) to begin the run... Would i need to reboot the emulator for each run?

Yeah reset the game. Both soft and and resets are fine.

So savestate even just to return to start screen is forbidden? :'( But the time begins well at "tries" appaers... So sad!