should i use handheld mode, pro controller, joycons w/ wrist straps, or joycons attached to joycon grip controller to play the game in a speedrun. i would think wrist straps for better movement such as rolling with motion controls is the fastest movement method?

Just use joycons or whatever you feel most comfortable using.

I use joycons because I have smaller hands so they are comfortable to me. Joycons generally have better motion because you're only shaking with 1 hand rather than 2. Pro-controller however has larger buttons and sticks which some people prefer much more. I would recommend trying the two options but do not use joycon grip or handheld mode.

You can use whatever you feel comfortable with, I like to use the ProController.